B.J. Raji is out for the year with a torn biceps. You feel for him, of course, but this is a potentially huge loss for a defense that was expected to be much improved. A healthy Raji was believed to be an important part of growing young talent among the front seven as well as working with the addition of Julius Peppers. Again, crap.
Photo credit: By Mike Morbeck (Flickr: B.J. Raji) [CC-BY-SA-2.0 (http://creativecommons.org/licenses/by-sa/2.0)], via Wikimedia Commons